Antibiotic resistance and replication. (A) Among the samples taken within 5 days after antibiotic treatment, the antibiotic resistance potential of each sample is correlated with its mean replication index value (Pearson’s r = 0.39, P = 0.03). (B) In infants that did not receive antibiotics after the first week of life, bacteria harboring at least one major facilitator superfamily (MFS) transporter gene had significantly higher iRep values (Mann-Whitney U = 827,176.0, P = 1.55 × 10−5), and this pattern is apparent within the members of the Firmicutes phylum (Mann-Whitney U = 136,756.0, P = 0.0002).