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. 2018 Jan 8;8:87. doi: 10.1038/s41598-017-18035-0

Table 2.

Indicate lesion type and mean ± standard deviation apparent diffusion coefficient (ADC) values by using different b value combinations before and after the gadolinium based contrast agent administration (G-CA).

b Value Protocol Tissue type
Malignant (N = 25) Benign (N = 7)
Pre-G-CA (x 10−3 mm2/s) Post-G-CA (x 10−3 mm2/s) Mean change (%) r/P Pre-G-CA (x 10−3 mm2/s) Post-G-CA (x 10−3 mm2/s) Mean change (%) r/P
ADC0,200,400,600,800 0.93 ± 0.28 0.92 ± 0.28 −1.60 ± 4.51 0.975/0.042 1.47 ± 0.25 1.46 ± 0.30 −1.49 ± 5.07 1.00/ns.
ADC400,600,800 0.76 ± 0.24 0.76 ± 0.27 0.21 ± 13.3 0.902/ns. 1.25 ± 0.17 1.30 ± 0.33 3.23 ± 15.80 0.857/ns.
ADC0,200,400 1.12 ± 0.34 1.08 ± 0.28 −1.43 ± 8.61 0.947/ns. 1.71 ± 0.34 1.62 ± 0.29 −4.73 ± 5.46 0.750/ns.
ADC0,200,800 0.92 ± 0.28 0.90 ± 0.27 −1.57 ± 4.64 0.969/0.040 1.45 ± 0.24 1.44 ± 0.30 −1.50 ± 6.00 1.000/ns.
ADC0,400,800 0.94 ± 0.28 0.92 ± 0.27 −1.36 ± 4.82 0.970/ns. 1.48 ± 0.25 1.46 ± 0.30 −1.79 ± 5.61 0.964/ns.
ADC0,200 1.25 ± 0.37 1.23 ± 0.30 0.40 ± 9.60 0.925/ns. 1.87 ± 0.35 1.78 ± 0.34 −4.62 ± 4.55 0.929/ns.
ADC0,800 0.94 ± 0.28 0.92 ± 0.27 −1.36 ± 4.82 0.970/ns. 1.48 ± 0.25 1.46 ± 0.30 −1.79 ± 5.61 0.964/ns.
ADC200,800 0.73 ± 0.23 0.69 ± 0.23 −3.32 ± 24.0 0.875/ns. 1.17 ± 0.18 1.19 ± 0.35 0.31 ± 20.8 0.929/ns.

ADC = Apparent Diffusion Coefficient; G-CA = gadolinium based intravenous contrast agent; Pre-G-CA = measurement before the intravenously administered contrast agent; Post-G-CA = measurement after the intravenously administered contrast agent.