Table 1.

Association of IFNAR1 rs72552343 and tuberculosis susceptibility

Cohort	Genotype	HC^a	TB	Multiplicative		Dominant
				p ^b	OR (95% CI)^c	p	OR (95% CI)
Discovery	TCC/TCC	1378 (95.4)	1499 (97.8)	0.0002	0.46 (0.31–0.70)	0.0003	0.47 (0.30–0.71)
	TCC/DEL	66 (4.6)	34 (2.2)
	DEL/DEL	1 (0.0)	0 (0.0)
Validation	TCC/TCC	1043 (96.2)	819 (98.4)	0.004	0.41 (0.21–0.76)	0.004	0.40 (0.21–0.75)
	TCC/DEL	41 (3.8)	13 (1.6)
	DEL/DEL	0 (0.0)	0 (0.0)
Combined	TCC/TCC	2421 (95.7)	2318 (98.0)	<0.0001	0.45 (0.32–0.64)	<0.0001	0.45 (0.32–0.64)
	TCC/DEL	107 (4.3)	47 (2.0)
	DEL/DEL	1 (0.0)	0 (0.0)

^a Number of samples with genotype frequency shown in parentheses

^b Significant p values (<0.05) are shown in bold

^c OR odds ratio, numbers in parentheses following OR are 95% confidence intervals