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. 2017 Oct 20;46(1):146–158. doi: 10.1093/nar/gkx958

Figure 4.

Figure 4.

Telomeric transcription is repressed by Snail1. (A) RT-qPCR showing the changes in expression of TERRA transcripts from different chromosomes (chr2q, chr11q or chr18q) in control MSC, Snail1KO MSC or Snail1KO+Snail1-HA MSC. Data represent the mean ± SEM of three independent experiments. *P < 0.05; **P < 0.01. (B, C) Levels of Snail1 and chr18q TERRA (B) or h2q and hXqY TERRA (C) were assessed by RT-qPCR in CAFs control (CT) and Snail1 KO (B) or in RWP-1 cells stably expressing Snail1-HA (C). **P < 0.01; *P < 0.05; P values higher than 0.05 are indicated.