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. Author manuscript; available in PMC: 2018 Jan 9.
Published in final edited form as: Toxicol Appl Pharmacol. 2017 Feb 11;320:26–31. doi: 10.1016/j.taap.2017.02.009

Fig. 2.

Fig. 2

TD-induced ER stress in iCell Neurons. A. iCell neurons were treated with amprolium (0 or 1 mM). At specified times after the treatment, the lysates of the iCell neuron samples were collected. The expressions of GRP78, XBP-1, CHOP, p-eIF2α, caspase-12, and ATF6 were determined by immunoblotting. B. The relative amounts of GRP78, CHOP, p-eIF2α, cleaved caspase-12, and ATF6 were measured microdensitometrically and normalized to the expression of actin. The experiment was replicated three times, and the results were expressed as the mean ± SEM. *p < 0.05, statistically significant difference from untreated control groups.