Table 1.
Diet containing G007-LK (100 mg/kg) | ||||||
---|---|---|---|---|---|---|
Sex | t1/2 (h) | Cmax (ng/mL) | AUC(0-t) (ng/mL*h) | AUC(0-∞) (ng/mL*h) | Fa (%) | Fb (%) |
Female | 4.17 | 762.50 | 4119.80 | 4770.32 | 22.22 | 20.69 |
t1/2: half life time, Cmax: maximum plasma concentration, AUC(0–t): The integral of the concentration–time curve to time t, AUC(0–∞): The integral of the concentration–time curve to time ∞, F: bioavailability
aThe bioavailability was calculated as F (%) = (Doseiv × AUCpo(0–t))/(Dosepo × AUCiv(0–t) × 100%
bThe bioavailability was calculated as F (%) = (Doseiv × AUCpo(0–∞))/(Dosepo × AUCiv(0–∞) × 100%