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. 2018 Jan 9;51:3. doi: 10.1186/s40659-017-0151-6

Table 1.

Pharmacokinetic parameters after administration of G007-LK enriched diet (n = 25 mice)

Diet containing G007-LK (100 mg/kg)
Sex t1/2 (h) Cmax (ng/mL) AUC(0-t) (ng/mL*h) AUC(0-∞) (ng/mL*h) Fa (%) Fb (%)
Female 4.17 762.50 4119.80 4770.32 22.22 20.69

t1/2: half life time, Cmax: maximum plasma concentration, AUC(0–t): The integral of the concentration–time curve to time t, AUC(0–∞): The integral of the concentration–time curve to time ∞, F: bioavailability

aThe bioavailability was calculated as F (%) = (Doseiv × AUCpo(0–t))/(Dosepo × AUCiv(0–t) × 100%

bThe bioavailability was calculated as F (%) = (Doseiv × AUCpo(0–))/(Dosepo × AUCiv(0–) × 100%