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. 2018 Jan 8;6:5. doi: 10.1186/s40478-017-0503-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Ring doughnut charts visualizing distributions of codon 129 genotypes, resPrP^Sc types and disease phenotypes among iCJD and sCJD cases examined. a whole iCJD cohort; inner circle: percent distribution of codon 129 genotype (MM, MV, VV); intermediate circle: distribution of resPrP^Sc types (T1, T2, Ti, Ti ± 2, T1 + 2); outer circle: distribution of histopathological phenotype. b GH-iCJD, legend as a; c DM-iCJD, legend as a; d sCJD. T1: type 1; Ti: type intermediate; T2: type 2; Ti + 2: type i + 2; T1 + 2: type 1 + 2; n: number of cases; na: not available; Atyp.: atypical; Undet.: undetermined. Percentages refer to the distribution of codon 129 genotype