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. 2018 Jan 9;17:2. doi: 10.1186/s12934-017-0852-0

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Comparison of iFP764 and iO548 metabolic networks of C. salexigens. a Distribution of genes in each of 10 functional categories (COG) in the iOA584 and iFP764 metabolic networks. Each functional category was represented with one color. The number of new genes associated to reaction (ORF) in the iFP764 are indicated by the lighter portion at the far right side of each bar. b Graphic representation of iOA584 (left) and iFP764 (right) metabolic networks. The colors and letters represent the functional categories of genes (COG) associated to reactions. Nodes are gene-enzyme associated reactions (squares) and metabolites (circles). Edges are represented by arrows which indicate the participation of metabolite in a reaction and its directionality (consumed or produced). The representation was performed by using Cytoscape (3.2). The connectivity problem in the iOA584 model is evidenced by the disconnected reactions and metabolites from the central network