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. Author manuscript; available in PMC: 2018 Jan 9.
Published in final edited form as: Neuroscience. 2017 Feb 8;348:63–72. doi: 10.1016/j.neuroscience.2017.01.050

Fig. 3.

Fig. 3

Raw and integrated (∫) recordings of the abdominal (AbN), cervical vagus (cVN), and phrenic nerve (PN) activities of an in situ preparation, representative of the group, showing the changes in baseline respiratory parameters after bilateral injections of the isoguvacine (arrows) into the KF. The two injections were completed within two minutes, and after the second injection there was a marked reduction in the cVN post-inspiratory (post-I) activity. These maximal effects lasted between 1 and 5 min, after which there was a recovery of the cVN post-inspiratory activity. Average values are presented for PN burst frequency (B) and amplitude (C), time of inspiration (D) and expiration (E), cVN inspiratory (F) and post-inspiratory (G) area under the curve (AUC) and AbN activity during E1 (H) and E2 (I) phases. Bars represent means ± S.E.M. n = 13, * represents P < 0.05.