Table 2.
Plasma levels (pmol/mL) and urinary excretion rates (nmol/min) of catechols before and after eating olives
| Time (min) | |||||||
|---|---|---|---|---|---|---|---|
| BL | 15’ | 30’ | 45’ | 60’ | 120’ | 180’ | 240’ |
| Catechol | |||||||
| DHPG | |||||||
| 5.6 ± 0.4 | 5.6 ± 0.5 | 7.5 ± 1.0 | 7.7 ± 0.9 | 6.9 ± 0.6 | 5.7 ± 0.4 | 6.0 ± 0.3 | 6.2 ± 0.3 |
| NE | |||||||
| 1.3 ± 0.3 | 1.1 ± 0.2 | 1.4 ± 0.4 | 1.3 ± 0.3 | 1.2 ± 0.2 | 1.4 ± 0.2 | 1.2 ± 0.3 | 1.2 ± 0.2 |
| DOPA | |||||||
| 7.8 ± 0.7 | 6.9 ± 0.6 | 7.5 ± 0.9 | 9.2 ± 0.9 | 7.4 ± 0.7 | 7.4 ± 0.6 | 7.6 ± 0.6 | 7.6 ± 0.6 |
| EPI | |||||||
| 0.05 ± 0.01 | 0.05 ± 0.01 | 0.06 ± 0.01 | 0.05 ± 0.01 | 0.06 ± 0.01 | 0.05 ± 0.01 | 0.05 ± 0.01 | 0.07 ± 0.02 |
| Cys‐DOPA | |||||||
| 5.7 ± 1.5 | 5.2 ± 1.5 | 5.4 ± 1.6 | 5.3 ± 1.6 | 5.6 ± 1.5 | 5.1 ± 0.9 | 5.2 ± 1.1 | 5.1 ± 1.1 |
| DOPET | |||||||
| 0.04 ± 0.01 | 0.40 ± 0.19 | 0.64 ± 0.17 | 0.40 ± 0.09 | 0.32 ± 0.04 | 0.11 ± 0.04 | 0.07 ± 0.01 | 0.05 ± 0.01 |
| DA | |||||||
| 0.09 ± 0.03 | 0.13 ± 0.07 | 0.12 ± 0.05 | 0.12 ± 0.04 | 0.12 ± 0.04 | 0.10 ± 0.04 | 0.07 ± 0.02 | 0.07 ± 0.02 |
| DOPAC | |||||||
| 8.7 ± 1.2 | 60 ± 23 | 256 ± 63 | 326 ± 74 | 290 ± 44 | 124 ± 27 | 37 ± 7 | 21 ± 3 |
| Cys‐DA | |||||||
| 0.08 ± 0.04 | 0.08 ± 0.05 | 0.07 ± 0.05 | 0.08 ± 0.05 | 0.08 ± 0.06 | 0.08 ± 0.05 | 0.08 ± 0.05 | 0.06 ± 0.04 |
| Catechol | |||||||
| DHHC | |||||||
| 1.9 ± 1.4 | 3.4 ± 1.2 | 9.2 ± 1.9 | 10.3 ± 2.0 | 8.9 ± 1.6 | 3.9 ± 1.5 | 2.1 ± 1.0 | 1.5 ± 0.9 |
| Urinary excretion rates (nmol/min) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Condition | DHPG | NE | DOPA | EPI | Cys‐DOPA | DOPET | DA | DOPAC | Cys‐DA | DHHC |
| BL | 0.31±0.10 | 0.19±0.07 | 0.06±0.01 | 0.04±0.01 | 0.56±0.21 | 0.02±0.01 | 0.97±0.23 | 2.27±0.66 | 0.03±0.01 | 0.56±0.23 |
| Post | 0.46±0.12 | 0.13±0.04 | 0.08±0.02 | 0.03±0.01 | 0.48±0.15 | 0.25±0.07 | 1.02±0.31 | 17.3±5.9 | 0.02±0.01 | 1.88±0.59 |
Mean values expressed ±SEM. For plasma catechols, items in bold indicate significant differences (P < 0.05) from baseline (BL) by Dunnett's post‐hoc test after repeated measures analysis of variance. Urinary excretion rates before olive ingestion were based on a presumed 94‐min interval from the previous void to the BL sample collection.