Table 2.
The maternal characteristics and 75-g OGTT results during pregnancy in terms of the different diagnostic criteria
| Variables | All subjects (n = 306) |
Postpartum OGTT | ||
|---|---|---|---|---|
| JSOG criteria (n = 116) |
IADPSG Criteria (n = 190) |
P value * | ||
| Maternal age (years) | 33.0 ± 5.1 | 33.2 ± 4.8 | 32.9 ± 5.2 | 0.52 |
| Nulliparous (%) | 136 (44%) | 46 (40%) | 90 (47%) | 0.19 |
| Family history of diabetes (%) | 124 (41%) | 47 (41%) | 77 (41%) | 1.0 |
| Pre-pregnancy BMI (kg/m2) | 23.5 ± 4.8 | 24.0 ± 4.9 | 23.2 ± 4.8 | 0.14 |
| Pre-pregnancy BMI ≥25 kg/m2 | 92 (30%) | 41 (35%) | 52 (27%) | 0.14 |
| GA at OGTT (weeks) | 24.2 ± 6.7 | 23.9 ± 7.6 | 24.4 ± 6.1 | 0.60 |
| OGTT results during pregnancy | ||||
| Fasting PG (mg/dl) | 86 ± 10 | 88 ± 11 | 85 ± 10 | 0.0046 |
| 1-h PG (mg/dl) | 186 ± 27 | 197 ± 23 | 179 ± 26 | <0.0001 |
| 2-h PG (mg/dl) | 161 ± 26 | 168 ± 22 | 156 ± 27 | 0.0001 |
| HbA1c (%) | 5.5 ± 0.4 (n = 269) | 5.5 ± 0.4 (n = 108) | 5.5 ± 0.4 (n = 158) | 0.94 |
| Insulin therapy during pregnancy (%) | 162 (53%) | 54 (47%) | 108 (58%) | 0.057 |
| Weight gain during pregnancy (kg) | 7.3 ± 5.1 | 6.9 ± 5.8 | 7.5 ± 4.6 | 0.37 |
| Mean follow-up period (weeks) (median, range) | 68 ± 61 (57, 7–292) | 83 ± 81 (58, 7–292) | 59 ± 43 (57, 7–164) | 0.0006 |
| At least two follow-up OGTTs (%) | 229 (75%) | 81 (70%) | 148 (78%) | 0.079 |
| More than 12 months of follow-up OGTTs (%) | 165 (54%) | 61 (53%) | 104 (55%) | 0.19 |
| Women who developed diabetes (%) | 32 (10.5%) | 11 (9.5%) | 21 (11.1%) | 0.66 |
* P values represent comparisons between the JSOG and IADPSG criteria using Student’s t-test or a chi-squared test
OGTT oral glucose tolerance test, JSOG Japan Society of Obstetrics and Gynecology, IADPSG Internal Association of Diabetes and Pregnancy Study Group, BMI body mass index, GA gestational age, PG plasma glucose