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. 2018 Jan 8;15:9. doi: 10.1186/s12974-017-1045-9

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Reduced macrophage infiltration in CCI mouse ipsilateral DRG and sciatic nerve following WWL70 treatment. The numbers of F4/80 positive macrophages in the DRG (a) and sciatic nerve (b) in mice treated with WWL70 (10 mg/kg) after CCI were remarkably reduced compared to the CCI/vehicle group. (c, d) Quantification of the F4/80-positive cells in DRG and sciatic nerve (mean ± S.E.M., n = 8/group). Scale bar = 50 μm. Merge represents co-localization of DAPI (blue) with F4/80 (green)