Figure 2.

Assessment of success or failure at preventing emergence cough following extubation under the predetermined remifentanil Ce in consecutive patients determined by Dixon’s up-and-down methods.

Notes: The mean EC₅₀ of remifentanil Ce for preventing emergence cough was calculated from crossover pairs of successes (filled circles) and failures (open circles) in (A) 23 male patients and (B) 22 female patients. The mean ± standard deviation EC₅₀ values of remifentanil Ce values were 2.56±0.37 ng/mL in males and 1.56±0.26 ng/mL in females. EC₅₀ is defined as effective concentration for preventing emergence cough following extubation in 50% of patients.

Abbreviation: Ce, effect-site concentration.