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. 2018 Jan 5;11:253–269. doi: 10.2147/OTT.S148394

Table S2.

GO annotation significantly related to target genes

Term Count P-value Genes
Lymphangiogenesis 3 0.0043 PPP3CB, FLT4, BMPR2
Transmembrane receptor protein serine/threonine kinase activity 3 0.0069 LTBP4, LTBP1, BMPR2
Feeding behavior 7 0.0078 MCHR1, PPYR1, OPRD1, GLS, ASIP, PHF21A, IAPP
RNA polymerase II carboxy-terminal domain kinase activity 3 0.0043 GTF2H1, CDK9, GTF2H4
Copper chaperone activity 2 0.0077 PARK7, CCS
Fatty acid elongation, saturated fatty acid 2 0.0077 ELOVL4, ELOVL6
Fatty acid elongation 3 0.0029 ELOVL2, ELOVL4, ELOVL6
Intracellular receptor signaling pathway 13 0.0090 ZNF536, CCNE1, DCBLD2, PGR, MAP3K7, GPR56, ITCH, NOD1, KANK2, THRA, PARK7, RXRB, DDX5
Negative regulation of protein complex assembly 7 0.0071 THRA, HEY2, SPTAN1, MAP3K7, OPRD1, MAPRE1, PARK7
Positive regulation of stress-activated MAPK cascade 8 0.0064 IL1A, FLT4, MAP3K10, TNFSF11, NOD1, HIPK2, MAP3K7, STK25
Lymph vessel morphogenesis 3 0.0059 PPP3CB, FLT4, BMPR2
Intrinsic apoptotic signaling pathway in response to hydrogen peroxide 2 0.0077 PARK7, STK25
Paracrine signaling 2 0.0077 TNFSF11, PGR
Sertoli cell development 3 0.0059 DMRT1, ARID4B, SDC1
Positive regulation of stress-activated protein kinase signaling cascade 8 0.0067 IL1A, FLT4, MAP3K10, TNFSF11, NOD1, HIPK2, MAP3K7, STK25
Serine/threonine protein kinase complex 5 0.0072 GTF2H1, CDK9, MAP3K7, RB1CC1, GTF2H4
Protein kinase complex 7 0.0026 GTF2H1, CDK9, CCNE1, PRKAB2, GTF2H4, MAP3K7, RB1CC1

Abbreviation: GO, gene ontology.