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. 2018 Jan 8;16:3. doi: 10.1186/s12969-017-0217-6

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — ELISA confirmation of secreted proteins on synovial fluid samples, from the same patients used in the transcriptome analysis. Synovial fluid from all 12 persistent and the combined group of all 11 extended and extended-to-be samples were assayed for levels of specific proteins. All 5 genes were more highly expressed by microarray in FLS of extended-to-be. All 5 proteins trended towards increased expression in the synovial fluid of extended and extended-to-be, but only CD14 and ANKRD44 differences reached significance at p-value <0.05