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. 2018 Feb;62:146–158. doi: 10.1016/j.neurobiolaging.2017.10.005

Table 3.

Comparisons between the LBC1921 (age ∼92 years) and the LBC1936 (age ∼73 years) on continuous health (biomarker) measures

Measure Sample mean (SD)
Difference test
LBC1921 (n = 42) LBC1936 (n = 126) t p ds
Blood hemoglobin (g/L) 124.43 (11.95) 139.49 (13.48) −6.79 <0.001 1.21
White cell count (×109/L) 7.01 (2.05) 6.60 (1.47) 1.18 0.24 0.21
Fibrinogen (g/L) 3.16 (0.76) 3.33 (0.66) −1.24 0.22 0.22
D-dimer (ng/dL) 376.91 (462.24) 206.71 (197.71) 1.98 0.055 0.35
eGFR (mL/min) 55.63 (12.33) 63.84 (3.93) −4.14 <0.001 0.74
HbA1c (DCCT) 5.61 (0.40) 5.74 (0.59) −1.58 0.12 0.28

Differences calculated using Welch's 2-sample t-test; d-values are Cohen's ds (see Lakens, 2013).

Key: eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin; LBC1921, Lothian Birth Cohort 1921; LBC1936, Lothian Birth Cohort 1936; SD, standard deviation.