Table 1.
Incidence rates of classical Hodgkin lymphoma (HL) overall and by selected histologic subtype, for Hispanics and whites, and race/ethnicity incidence rate ratios (IRR) and 95 % confidence intervals (CI), by gender and age, 1988–2004, California
| All HL | Nodular sclerosis HL | Mixed cellularity HL | ||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hispanics | Whites | Hispanic vs. White |
Hispanics | Whites | Hispanic vs. White |
Hispanics | Whites | Hispanic vs. White |
||||||||||||||||
| N | Rate* | 95% CI | N | Rate* | 95% CI | IRR | 95% CI | N | Rate* | 95% CI | N | Rate* | 95% CI | IRR | 95% CI | N | Rate* | 95% CI | N | Rate* | 95% CI | IRR | 95% CI | |
| TOTAL | ||||||||||||||||||||||||
| Age (10-year groups) | ||||||||||||||||||||||||
| 00–09 | 134 | 0.38 | 0.32–0.45 | 56 | 0.17 | 0.13–0.22 | 2.24 | 1.64–3.05 | 77 | 0.22 | 0.17–0.27 | 32 | 0.10 | 0.07–0.14 | 2.20 | 1.46–3.32 | 44 | 0.13 | 0.09–0.17 | 13 | 0.04 | 0.02–0.07 | 3.25 | 1.75–6.03 |
| 10–19 | 465 | 1.54 | 1.40–1.69 | 778 | 2.43 | 2.26–2.61 | 0.63 | 0.56–0.71 | 360 | 1.19 | 1.07–1.32 | 632 | 1.97 | 1.82–2.13 | 0.60 | 0.53–0.69 | 54 | 0.18 | 0.13–0.23 | 67 | 0.21 | 0.16–0.27 | 0.86 | 0.60–1.23 |
| 20–29 | 648 | 1.98 | 1.83–2.14 | 2,071 | 5.65 | 5.41–5.90 | 0.35 | 0.32–0.38 | 474 | 1.45 | 1.32–1.59 | 1,650 | 4.51 | 4.29–4.73 | 0.32 | 0.29–0.36 | 93 | 0.29 | 0.23–0.35 | 192 | 0.52 | 0.45–0.60 | 0.56 | 0.44–0.71 |
| 30–39 | 415 | 1.44 | 1.31–1.59 | 1,842 | 3.89 | 3.72–4.07 | 0.37 | 0.33–0.41 | 278 | 0.96 | 0.85–1.08 | 1,429 | 3.01 | 2.86–3.17 | 0.32 | 0.28–0.36 | 79 | 0.28 | 0.22–0.35 | 203 | 0.43 | 0.38–0.50 | 0.65 | 0.50–0.84 |
| 40–49 | 254 | 1.45 | 1.28–1.64 | 1,133 | 2.56 | 2.42–2.72 | 0.57 | 0.49–0.65 | 127 | 0.72 | 0.60–0.86 | 769 | 1.74 | 1.62–1.87 | 0.41 | 0.34–0.50 | 69 | 0.40 | 0.31–0.51 | 176 | 0.40 | 0.34–0.46 | 1.00 | 0.76–1.32 |
| 50–59 | 222 | 2.33 | 2.03–2.66 | 759 | 2.34 | 2.18–2.52 | 1.00 | 0.86–1.16 | 86 | 0.90 | 0.72–1.11 | 415 | 1.28 | 1.16–1.41 | 0.70 | 0.56–0.89 | 72 | 0.75 | 0.59–0.95 | 188 | 0.58 | 0.50–0.67 | 1.29 | 0.99–1.70 |
| 60–69 | 207 | 3.65 | 3.17–4.18 | 792 | 3.23 | 3.01–3.46 | 1.13 | 0.97–1.32 | 62 | 1.09 | 0.84–1.40 | 334 | 1.36 | 1.22–1.52 | 0.80 | 0.61–1.05 | 85 | 1.50 | 1.20–1.86 | 226 | 0.92 | 0.80–1.05 | 1.63 | 1.27–2.09 |
| 70–79 | 171 | 5.46 | 4.67–6.35 | 774 | 3.94 | 3.66–4.22 | 1.39 | 1.17–1.64 | 54 | 1.74 | 1.30–2.27 | 270 | 1.37 | 1.21–1.55 | 1.27 | 0.95–1.70 | 56 | 1.75 | 1.32–2.28 | 246 | 1.25 | 1.10–1.42 | 1.40 | 1.05–1.87 |
| 80+ | 79 | 5.76 | 4.56–7.19 | 432 | 3.84 | 3.48–4.22 | 1.50 | 1.18–1.91 | 30 | 2.20 | 1.48–3.14 | 156 | 1.39 | 1.18–1.62 | 1.58 | 1.07–2.34 | 29 | 2.10 | 1.40–3.01 | 120 | 1.06 | 0.88–1.27 | 1.98 | 1.32–2.97 |
| Age groups | ||||||||||||||||||||||||
| 00–14 | 298 | 0.61 | 0.54–0.69 | 268 | 0.54 | 0.48–0.61 | 1.13 | 0.96–1.33 | 195 | 0.40 | 0.35–0.46 | 202 | 0.41 | 0.36–0.47 | 0.98 | 0.80–1.19 | 75 | 0.15 | 0.12–0.19 | 34 | 0.07 | 0.05–0.10 | 2.14 | 1.43–3.21 |
| 15–39 | 1,364 | 1.76 | 1.67–1.86 | 4,479 | 4.48 | 4.35–4.62 | 0.39 | 0.37–0.42 | 994 | 1.28 | 1.20–1.36 | 3,541 | 3.55 | 3.43–3.67 | 0.36 | 0.34–0.39 | 195 | 0.26 | 0.22–0.29 | 441 | 0.44 | 0.40–0.48 | 0.59 | 0.50–0.70 |
| 40–54 | 360 | 1.59 | 1.43–1.76 | 1,531 | 2.47 | 2.35–2.60 | 0.64 | 0.57–0.72 | 170 | 0.74 | 0.63–0.86 | 990 | 1.60 | 1.50–1.70 | 0.46 | 0.39–0.54 | 105 | 0.48 | 0.39–0.58 | 272 | 0.44 | 0.39–0.49 | 1.09 | 0.87–1.37 |
| 55+ | 573 | 4.30 | 3.94–4.68 | 2,359 | 3.35 | 3.21–3.49 | 1.28 | 1.17–1.41 | 189 | 1.43 | 1.23–1.66 | 954 | 1.36 | 1.28–1.45 | 1.05 | 0.90–1.23 | 206 | 1.52 | 1.32–1.76 | 684 | 0.97 | 0.90–1.04 | 1.57 | 1.34–1.83 |
| TOTAL | 2,595 | 2.02 | 1.93–2.11 | 8,637 | 2.96 | 2.90–3.02 | 0.68 | 0.65–0.71 | 1,548 | 1.01 | 0.95–1.07 | 5,687 | 1.99 | 1.93–2.04 | 0.51 | 0.48–0.54 | 581 | 0.55 | 0.50–0.61 | 1,431 | 0.47 | 0.45–0.50 | 1.17 | 1.06–1.29 |
| MALES | ||||||||||||||||||||||||
| Age (10-year groups) | ||||||||||||||||||||||||
| 00–09 | 100 | 0.56 | 0.45–0.68 | 38 | 0.22 | 0.16–0.30 | 2.55 | 1.75–3.70 | 57 | 0.32 | 0.24–0.41 | 18 | 0.10 | 0.06–0.17 | 3.20 | 1.88–5.44 | 36 | 0.20 | 0.14–0.28 | 10 | 0.06 | 0.03–0.11 | 3.33 | 1.65–6.72 |
| 10–19 | 243 | 1.54 | 1.35–1.75 | 376 | 2.27 | 2.05–2.52 | 0.68 | 0.58–0.80 | 175 | 1.11 | 0.95–1.29 | 282 | 1.71 | 1.51–1.92 | 0.65 | 0.54–0.78 | 37 | 0.23 | 0.17–0.32 | 46 | 0.28 | 0.20–0.37 | 0.82 | 0.53–1.27 |
| 20–29 | 343 | 1.92 | 1.72–2.13 | 1,045 | 5.52 | 5.19–5.87 | 0.35 | 0.31–0.39 | 217 | 1.22 | 1.06–1.39 | 779 | 4.13 | 3.85–4.43 | 0.30 | 0.25–0.34 | 75 | 0.42 | 0.33–0.53 | 129 | 0.68 | 0.57–0.81 | 0.62 | 0.46–0.82 |
| 30–39 | 219 | 1.45 | 1.26–1.65 | 982 | 4.07 | 3.82–4.33 | 0.36 | 0.31–0.41 | 131 | 0.86 | 0.72–1.03 | 696 | 2.88 | 2.67–3.10 | 0.30 | 0.25–0.36 | 51 | 0.33 | 0.25–0.44 | 149 | 0.62 | 0.53–0.73 | 0.53 | 0.39–0.73 |
| 40–49 | 151 | 1.72 | 1.45–2.02 | 663 | 2.97 | 2.75–3.20 | 0.58 | 0.49–0.69 | 69 | 0.78 | 0.61–0.99 | 398 | 1.78 | 1.61–1.97 | 0.44 | 0.34–0.57 | 48 | 0.56 | 0.41–0.75 | 128 | 0.57 | 0.48–0.68 | 0.98 | 0.71–1.37 |
| 50–59 | 130 | 2.84 | 2.37–3.37 | 477 | 2.97 | 2.71–3.25 | 0.96 | 0.79–1.16 | 43 | 0.94 | 0.68–1.26 | 236 | 1.47 | 1.29–1.67 | 0.64 | 0.46–0.89 | 38 | 0.83 | 0.59–1.14 | 128 | 0.80 | 0.67–0.95 | 1.04 | 0.72–1.49 |
| 60–69 | 123 | 4.75 | 3.94–5.67 | 464 | 4.01 | 3.66–4.39 | 1.18 | 0.97–1.45 | 39 | 1.50 | 1.06–2.05 | 192 | 1.66 | 1.43–1.91 | 0.90 | 0.64–1.27 | 44 | 1.72 | 1.25–2.30 | 138 | 1.19 | 1.00–1.41 | 1.45 | 1.03–2.03 |
| 70–79 | 96 | 7.33 | 5.93–8.97 | 387 | 4.54 | 4.10–5.02 | 1.61 | 1.29–2.02 | 27 | 2.06 | 1.35–3.01 | 134 | 1.58 | 1.32–1.87 | 1.30 | 0.86–1.97 | 34 | 2.55 | 1.76–3.57 | 120 | 1.41 | 1.17–1.68 | 1.81 | 1.24–2.65 |
| 80+ | 40 | 8.01 | 5.71–10.93 | 198 | 5.13 | 4.43–5.90 | 1.56 | 1.11–2.19 | 15 | 3.07 | 1.71–5.07 | 65 | 1.68 | 1.29–2.15 | 1.83 | 1.04–3.20 | 17 | 3.30 | 1.91–5.30 | 61 | 1.57 | 1.19–2.02 | 2.10 | 1.23–3.60 |
| Age groups | ||||||||||||||||||||||||
| 00–14 | 195 | 0.78 | 0.67–0.89 | 150 | 0.59 | 0.50–0.69 | 1.32 | 1.07–1.64 | 120 | 0.48 | 0.40–0.57 | 96 | 0.38 | 0.31–0.46 | 1.26 | 0.97–1.65 | 57 | 0.22 | 0.17–0.29 | 28 | 0.11 | 0.07–0.16 | 2.00 | 1.27–3.14 |
| 15–39 | 710 | 1.71 | 1.58–1.84 | 2,291 | 4.44 | 4.26–4.63 | 0.39 | 0.35–0.42 | 460 | 1.11 | 1.01–1.22 | 1,679 | 3.27 | 3.11–3.43 | 0.34 | 0.31–0.38 | 142 | 0.34 | 0.28–0.40 | 306 | 0.59 | 0.52–0.66 | 0.58 | 0.47–0.70 |
| 40–54 | 213 | 1.89 | 1.64–2.16 | 913 | 2.93 | 2.74–3.12 | 0.65 | 0.56–0.75 | 89 | 0.77 | 0.62–0.95 | 518 | 1.66 | 1.52–1.81 | 0.46 | 0.37–0.58 | 67 | 0.60 | 0.47–0.77 | 197 | 0.63 | 0.55–0.73 | 0.95 | 0.72–1.26 |
| 55+ | 327 | 5.69 | 5.05–6.39 | 1,276 | 4.14 | 3.91–4.37 | 1.37 | 1.22–1.55 | 104 | 1.83 | 1.47–2.25 | 507 | 1.63 | 1.49–1.78 | 1.12 | 0.91–1.39 | 114 | 2.02 | 1.65–2.46 | 378 | 1.23 | 1.10–1.36 | 1.64 | 1.33–2.02 |
| TOTAL | 1,445 | 2.40 | 2.24–2.56 | 4,630 | 3.22 | 3.13–3.32 | 0.75 | 0.70–0.79 | 773 | 1.05 | 0.96–1.16 | 2,800 | 1.95 | 1.88–2.02 | 0.54 | 0.50–0.58 | 380 | 0.73 | 0.64–0.83 | 909 | 0.63 | 0.59–0.67 | 1.16 | 1.03–1.31 |
| FEMALES | ||||||||||||||||||||||||
| Age (10-year groups) | ||||||||||||||||||||||||
| 00–09 | 34 | 0.20 | 0.14–0.28 | 18 | 0.11 | 0.07–0.18 | 1.82 | 1.03–3.22 | 20 | 0.12 | 0.07–0.18 | 14 | 0.09 | 0.05–0.14 | 1.33 | 0.67–2.64 | 8 | 0.05 | 0.02–0.09 | <5 | 0.02 | 0.00–0.05 | 2.50 | 0.66–9.42 |
| 10–19 | 222 | 1.54 | 1.35–1.76 | 402 | 2.60 | 2.35–2.86 | 0.59 | 0.50–0.70 | 185 | 1.29 | 1.11–1.49 | 350 | 2.26 | 2.03–2.51 | 0.57 | 0.48–0.68 | 17 | 0.12 | 0.07–0.19 | 21 | 0.14 | 0.08–0.21 | 0.86 | 0.45–1.62 |
| 20–29 | 305 | 2.06 | 1.83–2.30 | 1,026 | 5.78 | 5.43–6.15 | 0.36 | 0.31–0.40 | 257 | 1.74 | 1.53–1.96 | 871 | 4.91 | 4.59–5.25 | 0.35 | 0.31–0.41 | 18 | 0.12 | 0.07–0.19 | 63 | 0.36 | 0.27–0.46 | 0.33 | 0.20–0.56 |
| 30–39 | 196 | 1.44 | 1.24–1.66 | 860 | 3.71 | 3.46–3.96 | 0.39 | 0.33–0.45 | 147 | 1.07 | 0.90–1.26 | 733 | 3.16 | 2.93–3.39 | 0.34 | 0.28–0.40 | 28 | 0.22 | 0.14–0.31 | 54 | 0.23 | 0.18–0.31 | 0.96 | 0.61–1.51 |
| 40–49 | 103 | 1.18 | 0.96–1.44 | 470 | 2.15 | 1.96–2.35 | 0.55 | 0.44–0.68 | 58 | 0.66 | 0.50–0.85 | 371 | 1.70 | 1.53–1.88 | 0.39 | 0.29–0.51 | 21 | 0.25 | 0.15–0.38 | 48 | 0.22 | 0.16–0.29 | 1.14 | 0.68–1.90 |
| 50–59 | 92 | 1.86 | 1.50–2.28 | 282 | 1.73 | 1.53–1.94 | 1.08 | 0.85–1.36 | 43 | 0.87 | 0.63–1.17 | 179 | 1.10 | 0.95–1.28 | 0.79 | 0.57–1.10 | 34 | 0.69 | 0.48–0.96 | 60 | 0.37 | 0.28–0.47 | 1.86 | 1.22–2.84 |
| 60–69 | 84 | 2.73 | 2.18–3.38 | 328 | 2.52 | 2.25–2.81 | 1.08 | 0.85–1.38 | 23 | 0.75 | 0.47–1.12 | 142 | 1.10 | 0.93–1.30 | 0.68 | 0.44–1.06 | 41 | 1.33 | 0.95–1.80 | 88 | 0.67 | 0.54–0.83 | 1.99 | 1.37–2.88 |
| 70–79 | 75 | 4.12 | 3.24–5.17 | 387 | 3.46 | 3.13–3.83 | 1.19 | 0.93–1.52 | 27 | 1.50 | 0.99–2.19 | 136 | 1.22 | 1.02–1.44 | 1.23 | 0.81–1.86 | 22 | 1.18 | 0.74–1.79 | 126 | 1.13 | 0.94–1.34 | 1.04 | 0.66–1.64 |
| 80+ | 39 | 4.48 | 3.19–6.13 | 234 | 3.20 | 2.80–3.64 | 1.40 | 1.00–1.96 | 15 | 1.72 | 0.96–2.84 | 91 | 1.24 | 1.00–1.52 | 1.39 | 0.80–2.40 | 12 | 1.38 | 0.71–2.41 | 59 | 0.81 | 0.62–1.04 | 1.70 | 0.92–3.17 |
| Age groups | ||||||||||||||||||||||||
| 00–14 | 103 | 0.44 | 0.36–0.53 | 118 | 0.49 | 0.41–0.59 | 0.90 | 0.69–1.17 | 75 | 0.32 | 0.25–0.40 | 106 | 0.44 | 0.36–0.54 | 0.73 | 0.54–0.98 | 18 | 0.08 | 0.05–0.12 | 6 | 0.02 | 0.01–0.05 | 4.00 | 1.59–10.08 |
| 15–39 | 654 | 1.82 | 1.68–1.97 | 2,188 | 4.53 | 4.34–4.72 | 0.40 | 0.37–0.44 | 534 | 1.47 | 1.35–1.61 | 1,862 | 3.85 | 3.68–4.03 | 0.38 | 0.35–0.42 | 53 | 0.16 | 0.12–0.21 | 135 | 0.28 | 0.23–0.33 | 0.57 | 0.42–0.79 |
| 40–54 | 147 | 1.29 | 1.09–1.52 | 618 | 2.01 | 1.85–2.17 | 0.64 | 0.54–0.77 | 81 | 0.70 | 0.56–0.88 | 472 | 1.53 | 1.40–1.68 | 0.46 | 0.36–0.58 | 38 | 0.35 | 0.25–0.48 | 75 | 0.24 | 0.19–0.31 | 1.46 | 0.99–2.15 |
| 55+ | 246 | 3.28 | 2.87–3.72 | 1,083 | 2.73 | 2.57–2.90 | 1.20 | 1.05–1.38 | 85 | 1.15 | 0.91–1.43 | 447 | 1.14 | 1.04–1.26 | 1.01 | 0.80–1.27 | 92 | 1.18 | 0.94–1.45 | 306 | 0.77 | 0.68–0.86 | 1.53 | 1.21–1.93 |
| TOTAL | 1,150 | 1.72 | 1.61–1.84 | 4,007 | 2.73 | 2.65–2.82 | 0.63 | 0.59–0.67 | 775 | 0.99 | 0.91–1.07 | 2,887 | 2.04 | 1.96–2.12 | 0.49 | 0.45–0.53 | 201 | 0.40 | 0.34–0.46 | 522 | 0.32 | 0.29–0.35 | 1.25 | 1.06–1.47 |
*
Rates are per 100,000 and age adjusted to the 2000 US Standard Population (19 age groups–Census P25–1130); confidence intervals (Tiwari modification) are 95 % for rates
Bolded IRR and 95 % CI are statistically significant
To comply with California Cancer Registry confidentiality regulations, case counts fewer than 5 are not presented