Table 4.
Number of classical Hodgkin lymphoma cases, percentages with EBV-positive tumors, and adjusted EBV prevalence ratios (PR) and 95 % confidence intervals (CI), in patient demographic and tumor subgroups, for foreign-born and US-born Hispanics and whites, 1988–1997, California regions
| Characteristic | Foreign-born Hispanics
|
US-born Hispanics
|
Whites
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | % EBV+ | PR* | 95 % CI | N | % EBV+ | PR† | 95 % CI | N | % EBV+ | PR‡ | 95 % CI | |
| Age groups | ||||||||||||
| 0–14 | 7 | 85.7 | 1.7 | 1.03–2.7 | 22 | 72.7 | 2.8 | 1.7–4.5 | 21 | 28.6 | 1.4 | 0.8–2.6 |
| 15–39 | 36 | 41.7 | 1.0 | 75 | 22.7 | 1.0 | 394 | 18.5 | 1.0 | |||
| 40–54 | 14 | 64.3 | 1.4 | 0.7–2.6 | 27 | 29.6 | 1.5 | 0.8–3.2 | 104 | 11.5 | 0.6 | 0.3–0.97 |
| 55+ | 24 | 83.3 | 1.6 | 1.03–2.6 | 13 | 76.9 | 3.4 | 2.0–5.7 | 137 | 43.8 | 1.6 | 1.2–2.2 |
| p** | 0.005 | <.0001 | <.0001 | |||||||||
| Sex | ||||||||||||
| Male | 48 | 66.7 | 1.1 | 0.7–1.6 | 70 | 44.3 | 1.3 | 0.9–2.1 | 304 | 29.9 | 1.6 | 1.2–2.0 |
| Female | 33 | 54.6 | 1.0 | 67 | 29.9 | 1.0 | 352 | 17.1 | 1.0 | |||
| p** | 0.36 | 0.07 | <.0001 | |||||||||
| Histologic subtype | ||||||||||||
| NS | 40 | 42.5 | 1.0 | 95 | 30.5 | 1.0 | 493 | 15.2 | 1.0 | |||
| MC | 28 | 85.7 | 1.7 | 1.1–2.5 | 23 | 60.8 | 1.9 | 1.2–2.9 | 91 | 59.3 | 3.0 | 2.2–4.0 |
| Other | 13 | 69.3 | 1.2 | 0.7–2.0 | 19 | 42.1 | 1.1 | 0.6–1.8 | 72 | 30.6 | 1.4 | 0.9–2.1 |
| p** | 0.001 | 0.02 | <.0001 | |||||||||
| Census block group SES [16] | ||||||||||||
| Low | 50 | 60.0 | 0.9 | 0.6–1.4 | 59 | 50.9 | 1.5 | 0.97–2.4 | 52 | 26.9 | 1.0 | 0.7–1.6 |
| Mid-high | 31 | 64.5 | 1.0 | 78 | 26.9 | 1.0 | 604 | 22.7 | 1.0 | |||
| p** | 0.68 | 0.004 | 0.49 | |||||||||
| Ann Arbor stage [16] | ||||||||||||
| I/II | 45 | 51.1 | 1.0 | 72 | 40.3 | 1.0 | 402 | 20.7 | 1.0 | |||
| III/IV | 31 | 71.0 | 1.3 | 0.9–1.9 | 59 | 33.9 | 0.8 | 0.5–1.2 | 231 | 26.8 | 1.1 | 0.9–1.5 |
| Unknown | 5 | 100.0 | 1.5 | 1.02–2.3 | 6 | 33.3 | 0.5 | 0.2–1.1 | 23 | 26.1 | 1.1 | 0.6–1.8 |
| p** | 0.03 | 0.75 | 0.18 | |||||||||
| California region [16] | ||||||||||||
| Greater Bay area | 36 | 58.3 | 1.0 | 79 | 30.4 | 656 | 23.0 | |||||
| Southern CA | 45 | 64.4 | 1.1 | 0.7–1.5 | 58 | 46.6 | 1.2 | 0.8–1.8 | – | |||
| p** | 0.57 | 0.05 | ||||||||||
| Total | 81 | 61.7 | 137 | 37.2 | 656 | 23.0 | ||||||
*
Adjusted for age (4 groups), gender, histologic group (3 groups), Ann Arbor stage (3 groups), SES (2 groups), California region
†
Adjusted for age (4 groups), gender, histologic group (3 groups), Ann Arbor stage (3 groups), SES (2 groups), California region
‡
Adjusted for age (4 groups), gender, histologic group (3 groups), Ann Arbor stage (3 groups), SES (2 groups)
**
p value for Chi-square statistic