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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Ultrasound Med Biol. 2017 Nov 22;44(2):434–446. doi: 10.1016/j.ultrasmedbio.2017.09.021

Table 1.

The mean ± 95% confidence interval of the viscoelastic shell properties of Definity® at room temperature and physiological temperature obtained using the de Jong model (de Jong et al. 1992). The shell properties reported for Definity® at room temperature by other investigators (Faez et al. 2011; Goertz et al. 2007; Raymond et al. 2014) are listed for comparison along with the temperature and frequency-range used in the measurement.

Temperature Frequency range (MHz) Sp (N/m) Sf × 106 (kg/s)

Room temperature
 Present study 2 – 25 1.76 ± 0.18 0.21 ± 0.07

Goertz et al. (2007) 2 – 50 1.71 ± 0.24 0.015 ± 0.015
Faez et al. (2011) 5 – 15 1.64 ± 0.33 0.15 ± 0.02
Raymond et al. (2014) 2 – 25 1.76 ± 0.16 0.47 ± 0.05

Physiological temperature

 Present study 2 – 25 1.01 ± .07 0.04 ± 0.04