Table 2. Detection of tenofovir in hair, plasma and peripheral blood mononuclear cells in active and placebo participant arms in the US CDC PrEP safety study.

	TFV Detectable in Hair		TFV Detectable in Plasma matched to hair		TFV Detectable in Plasma matched to PBMCs		TFV Detectable in PBMCs
	No	Yes	No	Yes	No	Yes	No	Yes
Treatment	1	46	1	46	3	44	3	44
Placebo	40	1*	40	1*	10	1*	10	1*

TFV = tenofovir; PBMC = peripheral blood mononuclear cells;

*tenofovir detected in the same individual, on the same date, in the placebo arm across all three biomatrices