Table 5. Critical network genes.
| AMY | NAC | PFC | ||||||
|---|---|---|---|---|---|---|---|---|
| Gene | FC | pval | Gene | FC | pval | Gene | FC | pval |
| Bcl2 | 1.04 | 9.2E-03 | Adarb1 | -1.03 | 7.6E-03 | Atp2a2 | -1.07 | 3.7E-02 |
| Dll1 | 1.02 | 2.0E-02 | Gnai2 | 1.07 | 3.0E-02 | Camk2d | 1.04 | 1.3E-02 |
| Dnajc18 | -1.04 | 5.4E-03 | Gnao1 | -1.08 | 3.6E-02 | Col1a2 | 1.04 | 1.8E-03 |
| Dnajc28 | -1.03 | 3.7E-02 | Lamp2 | 1.07 | 2.8E-03 | Col5a1 | -1.05 | 3.1E-02 |
| Fgf9 | -1.06 | 7.5E-05 | Map2k4 | -1.05 | 4.6E-02 | Dcp1a | 1.04 | 3.5E-02 |
| Flot2 | 1.04 | 8.6E-03 | Mapt | -1.04 | 4.1E-02 | Fndc3b | 1.04 | 4.8E-02 |
| Hsp90ab1 | 1.09 | 1.4E-02 | Pgm1 | 1.08 | 1.1E-02 | Ick | -1.03 | 4.2E-02 |
| Hspa1a/1b | 1.04 | 2.2E-02 | Ppp2r1a | -1.06 | 2.5E-02 | Lamp2 | -1.06 | 3.6E-02 |
| Hspa4l | 1.03 | 4.9E-02 | Ptrpe | 1.08 | 1.4E-02 | Lin54 | -1.05 | 1.5E-02 |
| Htra2 | 1.05 | 1.2E-02 | Rap1b | 1.06 | 2.1E-02 | Mtmr3 | 1.04 | 5.6E-03 |
| M6pr | -1.10 | 2.3E-03 | Rela | 1.05 | 2.6E-02 | Polr2d | 1.04 | 1.7E-02 |
| Mapk6 | 1.04 | 2.9E-02 | Rhog | 1.06 | 1.9E-02 | Smad1 | -1.07 | 4.8E-03 |
| Ncstn | -1.05 | 1.2E-02 | Spcs3 | 1.04 | 3.2E-02 | Vldlr | 1.07 | 2.4E-02 |
| Nsmf | -1.09 | 4.2E-02 | Usp2 | -1.04 | 4.8E-02 | |||
| Onecut2 | 1.04 | 1.4E-02 | ||||||
| Pik3cd | 1.03 | 5.0E-02 | ||||||
| Rictor | -1.08 | 1.3E-02 | ||||||
| Smad3 | -1.11 | 9.0E-03 | ||||||
| Spred1 | -1.05 | 4.1E-02 | ||||||
| Suds3 | -1.06 | 1.2E-02 | ||||||
| Vamp8 | -1.04 | 3.4E-02 | ||||||
Genes dysregulated at 120h and present in at least one of the top three IPA networks derived from miRNAs dysregulated at 0 and 8h. Bold text indicates 120h dysregulated targets of miRNAs differentially expressed at 0 or 8h. Plain text indicates genes dysregulated at 120h that are not targets of 0 or 8h DE miRNAs. Hub genes derived from hierarchical clustering analyses are denoted with italics.