Table 2.
Prevalence of breast cancer intrinsic subtypes in different populations
| Race/ethnicity | Reference | Source | Subtypes definition |
Prevalence of breast cancer intrinsic subtypes |
|||
|---|---|---|---|---|---|---|---|
| Luminal A |
Luminal B |
HER2- enriched |
Triple Negative |
||||
| NHW | Plasilova (60) | The National Cancer Database (NCDB) | HR and HER2 | 74.80% | 9.70% | 4.10% | 11.40% |
| AA | 59.60% | 11% | 5.60% | 23.70% | |||
| API | 70.10% | 11.70% | 6.90% | 11.20% | |||
| US Latinas | 67.40% | 11.90% | 5.80% | 14.80% | |||
| Other/Unknown | 71.80% | 11.00% | 5.10% | 12.10% | |||
| NHW | Sineshaw (61) | The National Cancer Database (NCDB) | HR and HER2 | 66.80% | 8.90% | 3.80% | 10.20% |
| AA | 51.70% | 10.00% | 5.00% | 21.10% | |||
| API | 63.50% | 10.60% | 6.10% | 10.10% | |||
| US Latinas | 58.20% | 10.60% | 5.20% | 13.10% | |||
| Other/Unknown | 57.30% | 10.40% | 4.90% | 11.00% | |||
| NHW | Kurian (57) | California Cancer Registry | HR and HER2 | 71.60% | 16.90% | 11.50% | |
| AA | 53.00% | 22.40% | 24.60% | ||||
| API | 62.80% | 27.20% | 10.00% | ||||
| US Latinas | 59.30% | 24.00% | 16.70% | ||||
| NHW | Howlader (54) | SEER registries | HR and HER2 | 75.50% | 9.80% | 4.00% | 10.70% |
| AA | 60.20% | 11.40% | 6.00% | 22.50% | |||
| API | 71.10% | 12.30% | 6.90% | 9.70% | |||
| US Latinas | 68.20% | 11.40% | 5.70% | 14.70% | |||
| NHW | Chen (55) | SEER registries | HR and HER2 | 76% | 9.40% | 3.90% | 10.70% |
| AA | 60.70% | 10.90% | 5.70% | 22.60% | |||
| API | 71.80% | 11.90% | 6.60% | 9.70% | |||
| American Indian/Alaska Native | 71.40% | 12.10% | 4.70% | 11.90% | |||
| US Latinas | 68.70% | 11.60% | 5.70% | 14% | |||
| US Latinas | Banegas (53) | California Cancer Registry | HR and HER2 | 62.60% | 13.80% | 8.10% | 15.60% |
| NHW | Clarke (58) | California Cancer Registry | HR and HER2 | 62% | 9% | 4% | 9% |
| AA | 47% | 11% | 6% | 20% | |||
| API | 55% | 12% | 8% | 9% | |||
| US Latinas | 52% | 11% | 7% | 13% | |||
| NHW | Singh (66) | Hospital-based | HR and HER2 | 76,50% | 8,80% | 4,90% | 9,80% |
| AA | 58,90% | 11,40% | 6,80% | 22,80% | |||
| US Latinas | 59,00% | 11,80% | 9,50% | 19,70% | |||
| Chinese | 65,60% | 9,60% | 10,50% | 14,30% | |||
| Indian | 50,10% | 12,20% | 14,30% | 23,30% | |||
| NHW | Hines (62,88) | 4-Corners Breast Cancer Study | HR and HER2 | 70.60% | 8.40% | 5.90% | 15.10% |
| US Latinas | 50.70% | 17.30% | 14.50% | 17.40% | |||
| NHW | Kwan (65) | The Life After Cancer Epidemiology (LACE) study | HR and HER2 | 75.30% | 11.10% | 3.10% | 10.50% |
| AA | 59.40% | 9.00% | 3.20% | 28.40% | |||
| API | 71.40% | 15.90% | 6.40% | 6.30% | |||
| US Latinas | 68.50% | 14.20% | 6.60% | 10.70% | |||
| Other | 68.50% | 13.00% | 5.50% | 13.00% | |||
| NHW | Kroenke (63) | The Life After Cancer Epidemiology (LACE) study and Pathway study | HR and HER2 | 52.00% | 32.90% | 3.90% | 11.00% |
| AA | 31.40% | 34.40% | 4.50% | 29.70% | |||
| API | 47.70% | 36.80% | 6.60% | 8.90% | |||
| US Latinas | 45.50% | 35.80% | 4.70% | 14.00% | |||
| Other | 39.30% | 39.70% | 4.00% | 17.10% | |||
| NHW | Sweeney (64) | The Life After Cancer Epidemiology (LACE) study and Pathway study | PAM50 | 55.20% | 20.90% | 12.50% | 8.20% |
| AA | 43.20% | 8.70% | 11.60% | 30.40% | |||
| API | 55.20% | 21.50% | 12.40% | 5.00% | |||
| US Latinas | 44.20% | 24.00% | 15.60% | 11.60% | |||
| Latinas from Mexico | Lara-medina (67) | National Cancer Institute in Mexico | HR and HER2 | 76,90% | 23,10% | ||
| Latinas from Costa Rica | Srur-Rivero (69) | Hospital-based Costa Rica | HR and HER2 | 62.30% | 9,00% | 9.50% | 17.10% |
| Latinas from Brazil | de Macêdo Andrade (70) | Hospital-based Brazil | St Gallen 2011 | 23.79% | 44.61% | 14.50% | 17.10% |
| Latinas from Puerto Rico | Ortiz (72) | Hospital-based Puerto Rico | HR and HER2 | 61.80% | 13.30% | 7.50% | 17.30% |
| Latinas from Colombia | Serrano-Gómez (73) | National Cancer Institute in Colombia | HR and HER2 | 52.49% | 15.95% | 10.30% | 20.60% |
| St Gallen 2011 | 36.21% | 30.23% | 8.64% | 20.60% | |||
| St Gallen 2013 | 26.25% | 37.21% | 8.64% | 20.60% | |||
| Latinas from Colombia | Gómez (77) | Hospital-based Colombia | St Gallen 2011 | 22.30% | 56.40% | 9.10% | 12.20% |
| Latinas from Mexico | Martinez (68) | Clinical-based | HR and HER2 | 59.80% | 23.60% | 16.60% | |
| Latinas from Peru | Vallejos (78) | Hospital-based Peru | HR and HER2 | 49.3% | 13.20% | 16.2% | 21.3% |