Table 1.
Clinical and demographic characteristics, total and by FPC status
| Total (n=302) | FPC (n=185) | Familial non-FPC (n=117) | ||||
|---|---|---|---|---|---|---|
| Median age at PDAC (range) | 65 (37–93) | 66 (37–93) | 64 (38–87) | |||
|
| ||||||
| N | % | N | % | N | % | |
|
| ||||||
| Sex, male | 162 | 53.5 | 98 | 53.0 | 64 | 54.7 |
| Race | ||||||
| White | 293 | 97.7 | 180 | 98.4 | 113 | 96.6 |
| African American | 4 | 1.3 | 3 | 1.6 | 1 | 0.9 |
| American Indian/Alaska Native | 1 | 0.3 | 0 | 0 | 1 | 0.9 |
| Native Hawaiian | 1 | 0.3 | 0 | 0 | 1 | 0.9 |
| Multiracial | 1 | 0.3 | 0 | 0 | 1 | 0.9 |
| Missing | 2 | - | 2 | - | 0 | - |
| Ethnicity | ||||||
| Non-Hispanic/non-Latino | 291 | 99.7 | 176 | 100 | 115 | 99.1 |
| Hispanic/Latino | 1 | 0.3 | 0 | 0 | 1 | 0.9 |
| Missing | 10 | - | 9 | - | 1 | - |
| Ashkenazi Jewish heritage | ||||||
| No | 288 | 97.3 | 173 | 95.6 | 115 | 100 |
| Yes | 8 | 2.7 | 8 | 4.4 | 0 | 0 |
| Missing | 6 | - | 4 | - | 2 | - |
| Number PDAC per kindred | ||||||
| 2 | 239 | 79.2 | 128 | 69.2 | 111 | 94.9 |
| 3 | 44 | 14.6 | 38 | 20.5 | 6 | 5.1 |
| 4+ | 19 | 6.2 | 19 | 10.2 | 0 | 0 |
| PDAC stage | ||||||
| Resectable | 88 | 31.7 | 48 | 29.1 | 40 | 35.4 |
| Locally advanced | 77 | 27.7 | 46 | 27.9 | 31 | 27.4 |
| Metastatic | 113 | 40.6 | 71 | 43.0 | 42 | 37.2 |
| Missing | 24 | 20 | - | 4 | - | |