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. Author manuscript; available in PMC: 2019 Jan 8.
Published in final edited form as: Dev Cell. 2017 Dec 14;44(1):13–28.e3. doi: 10.1016/j.devcel.2017.11.011

Fig. 5. Junctional polarity of CM neuroepithelium is lost in the absence of Nf2 in either CM layer.

Fig. 5

Immunostaining of a TJ marker Pals1 (A) and an AJ marker β-catenin (B) in the CM neuroepithelium of P0 Nf2f/f, Nf2f/f;TRP1-Cre, Nf2f/f;MART1-Cre, Nf2f/f;Chx10-Cre mouse eyes. F-actin was visualized by staining with Alexa647-conjugated Phalloidin. Arrowheads point Pals1 localization in the TJs and β-catenin in the AJs, while arrows indicate diffused Pals1. (C) Summary of junctional protein distribution in wild-type (Nf2f/f) and Nf2-deficient mouse CM neuroepithelia.