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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Microcirculation. 2018 Jan;25(1):10.1111/micc.12431. doi: 10.1111/micc.12431

Figure 6. Role of KV1.5 in isoproterenol-induced dilation of human coronary arterioles from non-CAD and CAD subjects.

Figure 6

Isoproterenol-induced dilation was significantly reduced by selective KV1.5 channel blocker DPO-1 (10−6 M) in non-CAD arterioles (A). The dilation was also reduced by DPO-1 in CAD arterioles (B). *P<0.05 versus control; n=3–6 vessels/group. C, Dot density and associated box plots depicting the isoproterenol-induced maximal dilation of individual CAD arterioles used in two vessel groups for determining 4-AP- (Figure 4C) or DPO-1 (Figure 6B)-sensitive component of vasodilation, respectively. Mean dilation is indicated by red lines.