Shown are incidence rates and pointwise 95% CIs for the primary CVD outcome (panel A), all-cause death (panel B) and incident CKD (panel C) in the standard and intensive SBP groups by quintile of baseline DBP. The 95% CIs were calculated for incidence rates using the quadratic approximation to the Poisson log likelihood for the log-rate parameter. Lines are drawn between the incidence rates quintiles for the different quintiles for visual clarity, and do not represent fitted regression curves. The analysis of incident CKD patients was performed for patients with baseline eGFR ≥ 60 ml/min/1.73m2. There were too few events to provide a meaningful similar analysis for the composite kidney outcome.
SBP = systolic blood pressure; DBP = diastolic blood pressure; CVD = cardiovascular disease; CKD = chronic kidney disease; eGFR = estimated glomerular filtration rate; HR = hazard ratio; CI = confidence interval.