Table 1.
Maternal and infant characteristics of participants. BMI, body mass index; SIMD, Scottish Index of Multiple Deprivation; PMA, postmenstrual age; HC, head circumference.
| Methadone |
Control |
p value | |
|---|---|---|---|
| n = 20 | n = 20 | ||
| Maternal characteristics | |||
| Mean age (range)/years | 30 (23–41) | 30.9 (19–39) | 0.56 |
| Mean BMI (range) | 25.8 (21–41) | 23.2 (19–39) | 0.08 |
| Median SIMD decile (Interquartile range) | 3 (2–5) | 8 (6–10) | 0.012 |
| Infant characteristics | |||
| Mean PMA at birth (range)/weeks | 38+ 5 (37+ 1–41+ 0) | 39+ 1 (37+ 2–41+ 3) | 0.32 |
| Gender (M:F) | 10:10 | 13:7 | 0.52 |
| Mean birth weight (range)/g | 2721 (2150–3440) | 3349 (2346–4550) | < 0.01 |
| Mean birth weight z-score (sd) | − 1.062 (0.68) | 0.443 (0.86) | < 0.01 |
| Median (range) postnatal age at scan/days | 3 (1 to 21) | 13 (5 to 29) | 0.005 |
| Mean PMA at scan (range)/weeks | 39+ 2 (37+ 2–41+ 4) | 41+ 1 (39+ 0–42+ 2) | 0.004 |
| Mean HC at scan (range)/cm | 33.1 (31.2–35.0) | 35.9 (32.6–37.4) | < 0.01 |
| Mean HC z-score (sd) | − 0.523 (0.986) | 1.146 (0.837) | < 0.01 |