. 2018 Jan 5;8:1835. doi: 10.3389/fimmu.2017.01835

Table 2.

Absolute values for remodeling markers in the pulmonary parenchyma.

Remodeling markers	SAL	OVA	OVA anti-IL-17	OVA-LPS	OVA-LPS anti-IL-17
MMP-9 (cells/10⁴ μm²)	2.70 ± 0.46	8.11 ± 0.47^*	2.57 ± 0.36^**	16.50 ± 0.62^*,#	9.75 ± 0.43^**
MMP-12 (cells/10⁴ μm²)	0.32 ± 0.06	7.51 ± 0.48^*	1.36 ± 0.26^**	11.00 ± 1.96^*,#	1.62 ± 0.28^**
TIMP-1 (cells/10⁴ μm²)	1.11 ± 0.18	8.29 ± 0.85^*	2.72 ± 0.48^**	9.96 ± 0.95^*	3.95 ± 0.56^**
TGF-β (cells/10⁴ μm²)	1.65 ± 0.23	31.60 ± 2.22^*	19.84 ± 1.53^**	42.06 ± 1.91^*,#	8.35 ± 0.75^**
Collagen Fibers I (%)	12.16 ± 0.88	22.25 ± 2.16^*	13.58 ± 1.12^**	25.19 ± 1.48	20.08 ± 0.72^**
Collagen Fibers III (%)	0.89 ± 0.09	13.47 ± 0.62^*	8.17 ± 0.53^**	20.10 ± 0.80^*,#	7.89 ± 0.71^**
Decorin (%)	1.62 ± 0.29	52.68 ± 2.60^*	2.77 ± 0.43^**	55.66 ± 2.37^*	8.00 ± 0.92^**
Lumican (%)	14.03 ± 0.18	27.39 ± 1.02^*	21.64 ± 1.47^**	26.57 ± 0.68^*	15.33 ± 0.54^**
Actin (%)	8.05 ± 1.84	28.44 ± 1.99^*	12.80 ± 1.29^**	29.90 ± 1.93^*	6.9 ± 1.66^**
Biglycan (%)	4.13 ± 0.23	12.47 ± 0.71^*	5.39 ± 1.08^**	20.68 ± 2.83^*,#	5.00 ± 0.66^**
Fibronectin (%)	4.60 ± 0.47	40.27 ± 1.65^*	11.17 ± 1.06^**	48.56 ± 2.03^*,#	10.20 ± 0.78^**

Remodeling markers for MMP-9, MMP-12, TIMP-1, and TGF-β are expressed as positive cells/10⁴ μm². Collagen fibers I and II, decorin, lumican, actin, biglycan, and fibronectin are presented as volume fraction expressed as percentages of area (%).

*p < 0.05 in comparison with the SAL group.

**p < 0.05 in comparison with the OVA and OVA-LPS groups.

^#p < 0.05 in comparison with the OVA group.