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Concentration-dependent changes of APD, including APD30, APD50, and APD90, in the presence of increasing concentrations of tolterodine (A) and terodiline (B) under stimulation frequencies of 1 and 2 Hz. Tolterodine induced a concentration-dependent increase of APD90 and APD50 with minimal effects on APD30. Terodiline prolonged APD90, but shortened APD50 and APD30. *P < 0.05 versus values from vehicle.
