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. 2018 Jan 9;8:138. doi: 10.1038/s41598-017-18517-1

Table 1.

Sex differences in baseline characteristics of the study population.

Characteristics Men (n = 2,044) Women (n = 2,342) P values Cohen’s D
Demographics and life style factors
Age (years), mean (SD) 52.6 (14.4) 54.7 (12.9) <0.001 0.15
  Age (years), n (%) <0.001 0.29
  ≤39 460 (22.5) 319 (13.6)
  40–49 303 (14.8) 289 (12.4)
  50–59 489 (23.9) 784 (33.5)
  60–69 597 (29.2) 755 (32.2)
  ≥70 195 (9.6) 195 (8.3)
Education (years), n (%) 0.999 0.00
  ≤6 172 (8.4) 197 (8.4)
  07-Sep 496 (24.3) 570 (24.3)
  10-Dec 516 (25.2) 592 (25.3)
  >12 860 (42.1) 983 (42.0)
Residence, n (%) 0.870 0.01
  Urban 1,649 (80.7) 1,894 (80.9)
  Rural 395 (19.3) 448 (19.1)
  BMI (kg/m2), mean (SD) 24.2 (3.1) 23.0 (3.4) <0.001 0.37
BMI, n (%) <0.001 0.31
  <25 1,313 (64.2) 1,834 (78.3)
  25–30 649 (31.8) 412 (17.6)
  >30 82 (4.0) 96 (4.1)
Exercise habit, n (%) <0.001 0.26
  ≤3 times/week 857 (41.9) 1,281 (54.7)
  >3 times/week 1,187 (58.1) 1,061 (45.3)
Red Meat, n (%) <0.001 0.32
  <100  g/d 1,594 (78.0) 2,138 (91.3)
  ≥100  g/d 450 (22.0) 204 (8.7)
Smoking index, n (%) <0.001 0.85
Nonsmoker 1,162 (56.8) 2,314 (98.8)
  <400 294 (14.4) 12 (0.5)
  ≥400 588 (28.8) 16 (0.7)
Alcohol consumption, n (%) <0.001 0.54
  Non-drinker 1,548 (75.7) 2,315 (98.8)
  Light/Moderate drinker (1–350  g/week) 96 (4.7) 27 (1.2)
  Heavy drinker (≥351 g/week) 400 (19.6) 0 (0)
Comorbidities, n (%)
Hypertension 371 (18.2) 428 (18.3) 0.915 0.00
Diabetes mellitus 151 (7.4) 143 (6.1) 0.09 0.05
Coronary heart disease 94 (4.6) 111 (4.7) 0.826 0.00
Colonic polyps 1,030 (50.4) 919 (39.2) <0.001 0.22
Upper gastrointestinal diseasesa 151 (7.4) 164 (7.0) 0.622 0.02
Hepato-biliary diseasesb 92 (4.5) 86 (3.7) 0.165 0.04
Dyslipidemia 46 (2.3) 64 (2.7) 0.308 0.03
Rheumatologic diseasesc 46 (2.3) 43 (1.8) 0.331 0.03
Miscellaneousd 186 (9.1) 203 (8.7) 0.616 0.01
Medication, n (%)
NSAIDs 115 (5.6) 125 (5.3) 0.675 0.01
Corticosteroid 25 (1.2) 32 (1.4) 0.676 0.02
PPIs 123 (6.0) 169 (7.2) 0.112 0.05
Mucosal protective drugs 432 (21.1) 607 (25.9) <0.001 0.12
Antihypertension drugs 363 (17.8) 422 (18.0) 0.823 0.01
Hypoglycemic medications 149 (7.3) 138 (5.9) 0.62 0.05

Data are expressed as mean ± SD or number (percentage).

BMI body mass index, NSAIDs non-steroidal anti-inflammatory drugs, PPIs proton pump inhibitors.

aReflux esophagitis, atrophic gastritis, chronic gastritis, etc.

bCholelithiasis and fatty liver disease.

cRheumatoid arthritis and gout.

dOsteoporosis, arrhythmia, cerebral infarction, thyroid diseases, prostate diseases, etc.