Table 2.
For genes with a significant genetic association with investigated phenotypes, gene expression (ΔC T values) was analyzed in relation to genotype in colonic biopsies from the different subgroups
| Gene | SNP marker | Non-MC controls (number of controls) | p value | MC patients (number of patients) | p value | CC patients (number of patients) | p value | LC patients (number of patients) | p value |
|---|---|---|---|---|---|---|---|---|---|
| F11R | rs790055 | AA (2), AG (16), GG (39) | 0.676 | AA (3), AG (8), GG (14) | 0.482 | AA (2), AG (3), GG (5) | 0.428 | AA (0), AG (5), GG (9) | 0.851 |
| MAGI1 | rs17417230 | AA (6), AC (33), CC (19) | 0.480 | AA (6), AC (13), CC (6) | 0.621 | AA (2), AC (4), CC (4) | 0.590 | AA (4), AC (9), CC (1) | 0.825 |
| PTEN | rs1234224 | AA (21), AG (31), GG (6) | 0.978 | AA (10), AG (8), GG (7) | 0.081 | AA (4), AG (2), GG (4) | 0.103 | AA (5), AG (6), GG (3) | 0.535 |