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Pharmacokinetic parameters of 16-DHP in rat plasma after a single dose of 40 mg/kg of 16-DHP in six rats
| Pharmacokinetic parameters | Mean ± SD |
|---|---|
| Cmax (μg/L) | 289 ± 25 |
| tmax (h) | 0.38 ± 0.14 |
| t1/2 (h) | 2.5 ± 1.1 |
| AUC(0-t) (ng·h/mL) | 544 ± 73 |
| AUC(0-∞) (ng·h/mL) | 621 ± 116 |
| MRT(0-t) (h) | 2.2 ± 0.4 |
| MRT(0-∞) (h) | 3.4 ± 1.2 |
| CLz/F[L/(h · kg)] | 67 ± 13 |
| Vz/F(L/kg) | 229 ± 69 |
