Figure 1. Time course of hemoglobin level (Hb), white blood cell count (WBC), and platelet count (Plt) in the propositus before and during romiplostim administration.

Romiplostim was started at the dosage of 1 μg/kg/week, and this schedule was maintained for 3 months. Then, a dose of 4 μg/kg was given in a monthly administration. The platelet count had wide oscillations that derived, at least partially, from the variability of the time elapsed between the drug administrations and the measurements of blood count.