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Pharmacokinetic parameters of sparfloxacin in rats after an oral dose of 5 mg/kg a.
| Parameter | Mean (n=5) |
|---|---|
| t1/2α (h) | 1.81 |
| t1/2β (h) | 12.86 |
| AUC(0–t) (mg h/L) | 1.96 |
| AUC(0–∞) (mg h/L) | 2.17 |
| CL (L/h kg) | 2.31 |
| Cmax (ng/mL) | 346.06 |
| tmax (h) | 3.00 |
Two-compartment model analysis.
