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. 2012 Jan 25;2(3):200–205. doi: 10.1016/j.jpha.2012.01.005

Table 3.

Determination of atorvastatin in Lipitor® tablets (20 mg) by the proposed spectrofluorimetric methods.

Spectrofluorimetric method using acetate buffer (pH 3.4)
Spectrofluorimetric method using 5% acetic acid
Spectrofluorimetric method using methanol
Known concentration (μg/mL) Concentration found (μg/mL) Recovery (%) Known concentration (μg/mL) Concentration found (μg/mL) Recovery (%) Known concentration (μg/mL) Concentration found (μg/mL) Recovery (%)
2.00 1.97 98.62 2.00 1.99 99.75 1.00 1.03 102.92
2.50 2.59 103.44 3.00 3.02 100.60 1.50 1.47 98.03
3.00 3.15 105.10 4.00 4.02 100.53 2.00 1.96 98.18
3.50 3.59 102.67 2.50 2.54 101.47
4.00 3.99 99.95 3.00 3.12 104.09



Mean 101.96 100.29 100.94
N 5.00 3.00 5.00
SD 2.64 0.47 2.75
R.S.D. (%) 1.16 0.27 1.22