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Pharmacokinetic profile of NAT after intravenous administration in NZ rabbit.
| Parameters | Estimates |
|---|---|
| C0 (ng/mL) | 537±322 |
| AUC0−∞ (h*ng/mL) | 162±55 |
| t1/2 (h) | 1.4±0.4 |
| Vd (L/kg) | 8.3±2.8 |
| Cl (L/h/kg) | 6.6±1.9 |
Abbreviation: C0: concentration at time zero, AUC: area under the curve from 0 to ∞, Vd: volume of distribution, Cl: clearance, t1/2: terminal half-life, n=3.
