Table 1.
General nucleus of corticoids and different substitutions of different glucocorticoids drugs.
.
| Steroid name | Δ1, 2 | R6 | R9 | R11 | R16 | R17 | R21 |
|---|---|---|---|---|---|---|---|
| Hydrocortisone | Saturated | 3H | 3H | 3–OH | 3H | 3–OH | 3–OH |
| Cortisone | Saturated | 3H | 3H | åO | 3H | 3–OH | 3–OH |
| Corticosterone | Saturated | 3H | 3H | 3–OH | 3H | 3H | 3–OH |
| Fludrocortisone | Saturated | 3H | 3F | 3–OH | 3H | 3–OH | 3–OH |
| Prednisolone | Double bond | 3H | 3H | 3–OH | 3H | 3–OH | 3–OH |
| Prednisone | Double bond | 3H | 3H | åO | 3H | 3–OH | 3–OH |
| Methylprednisolone | Double bond | 3–CH3 | 3H | 3–OH | 3H | 3–OH | 3–OH |
| Prednisolone acetate | Double bond | 3H | 3H | 3–OH | 3H | 3–OH | 3–OCOCH3 |
| Dexamethasone | Double bond | 3H | 3F | 3–OH |
 (á isomer) |
3–OH | 3–OH |
| Betamethasone | Double bond | 3H | 3F | 3–OH |
(â isomer) |
3–OH | 3–OH |
| Beclomethasone | Double bond | 3H | 3Cl | 3–OH |
(â isomer) |
3–OH | 3–OH |
| Triamcinolone | Double bond | 3H | 3F | 3–OH | 3–OH | 3–OH | 3–OH |
| Triamcinolone acetonide | Double bond | 3H | 3F | 3–OH |  |
3–OH | |