Table 5.
The effects of change in body size between the ages of 15 and 30 on cancer and cardiovascular mortality in the Golestan Cohort Study
| Body size at ages 15 and 30 | Women | Men | ||||
|---|---|---|---|---|---|---|
|
| ||||||
|
All medical causes
a HR (95% CI) |
Cardiovascular HR (95% CI) |
Cancer HR (95% CI) |
All medical causesa HR (95% CI) |
Cardiovascular HR (95% CI) |
Cancer HR (95% CI) |
|
| Underweight at both | 0.82 (0.57–1.19) | 0.89 (0.55–1.44) | 0.96 (0.49–1.91) | 1.43 (0.91–2.25) | 1.80 (1.04–3.12)* | 0.35 (0.05–2.50) |
| Underweight only at 15 b | 0.95 (0.79–1.13) | 0.98 (0.77–1.24) | 0.83 (0.58–1.20) | 1.07 (0.89–1.30) | 1.15 (0.90–1.47) | 1.03 (0.69–1.54) |
| Normal at both | 1 | 1 | 1 | 1 | 1 | 1 |
| Obese only at 15 | 1.37 (1.12–1.68)** | 1.33 (1.00–1.75) | 1.56 (1.05–2.30)* | 1.37 (1.10–1.72)* | 1.29 (0.94–1.78) | 1.23 (0.76–2.01) |
| Obese only at 30 | 1.48 (1.20–1.83)** | 1.71 (1.30–2.25)** | 0.71 (0.40–1.27) | 1.46 (1.17–1.83)** | 1.57 (1.17–2.10)** | 1.27 (0.77–2.08) |
| Obese at both | 1.36 (1.14–1.62)** | 1.41 (1.12–1.78)* | 1.30 (0.90–1.86) | 1.23 (0.93–1.61) | 1.32 (0.93–1.88) | 1.34 (0.78–2.32) |
HR: hazard ratio; Cox regression models adjusted for age, smoking, socioeconomic status, ethnicity, residence, education, and opium. Body size analyses also adjusted for physical activity at the same age, and vice versa.
a
Excluding accidents, suicide and all other external causes of death.
b
There were not enough people in the group “underweight only at 30”
*
p<0.01,
**
p<0.001