Table 1.
Anthropometric and biochemical parameters in pediatric childhood-onset SLE subjects and in healthy controls
| Variables | SLE Group (n = 19) |
Control Group (n = 38) |
p |
|---|---|---|---|
| BMI (kg/m2)a | 24.6 (18.45–40.0) | 20.83 (15.96–31.24) | 0.001** |
| WC (cm)a | 79.66 ± 8.94 | 72.25 ± 7.88 | 0.001** |
| Folate (ng/L)c | 12.16 (5.8–19.25) | 13.91 (10.4–26.2) | 0.033* |
| Homocysteine (mmol/L)b | 8.62 ± 2.36 | 7.29 ± 1.80 | 0.019* |
| Total Cholesterol (mg/dL)c | 160.73 ± 42.76 | 152.75 ± 31.57 | 0.122 |
| HDL (mg/dL)c | 37.58 (27.0–61.0) | 44.14 (25.0–99.0) | 0.088 |
| LDL (mg/dL)c | 97.26 ± 26.16 | 89.75 ± 27.18 | 0.320 |
| Triglycerides (mg/dL)c | 152.42 (31.0–725.0) | 88.16 (25.0–226.0) | 0.003** |
| TNF - α (pg/mL)c | 8.65 ± 2.55 | 7.04 ± 2.39 | 0.002** |
| hs-CRP (mg/L)c | 4.41 (0.3–17.0) | 0.84 (0.3–4.6) | 0.000** |
*p < 0.05; post hoc Bonferroni **p < 0.005
Values expressed as mean ± standard deviation. The difference between means was calculated by ANCOVA adjusted by: agea; age, BMI and cyanocobalamin intakeb; age and BMIc
BMI = Body Mass Index, WC Waist Circumference, HDL High Density Lipoprotein, LDL = Low Density Lipoprotein, TNF – α Tumor Necrosis Factor – α, Hs-CRP high sensitive C- reactive protein