Table 5.
Pharmacokinetics parameter.
| Analyte | Drug | Statistics | Cmax (ng/mL) | AUC0-t (ng/mL h) | AUC0-inf (ng/mL h) |
|---|---|---|---|---|---|
| Itraconazole | Test (T) | Mean | 116.076 | 1522.932 | 1613.547 |
| RSD% | 62.0924 | 638.2451 | 688.1134 | ||
| Reference (R) | Mean | 128.940 | 1662.532 | 1756.137 | |
| RSD% | 61.1698 | 684.1797 | 719.9309 | ||
| 90% Confidence interval for the ratio of the means T/R (%) | 78.540–97.380 | 82.597–100.300 | 82.734–100.432 | ||
| Hydroxy itraconazole | Test (T) | Mean | 159.303 | 3343.322 | 3398.416 |
| RSD% | 60.6879 | 1549.1508 | 1549.0455 | ||
| Reference (R) | Mean | 175.738 | 3660.083 | 3757.739 | |
| RSD% | 63.0287 | 1559.1787 | 1544.6742 | ||
| 90% Confidence interval for the ratio of the means T/R (%) | 81.383–96.583 | 79.051–99.268 | 78.372–97.669 | ||