Table 1.
Merits of the proposed method in water, urine and plasma matrices for extraction and determination of CPZ.
Matrix | LOD (ng/mL) | LOQ (ng/mL) | RSD% (n=5, 10 ng/mL) |
Enrichment factor | Extraction percentage (%) | Linear range (ng/mL) | R2 | |
---|---|---|---|---|---|---|---|---|
Inter-day | Intra-day | |||||||
Water | 0.1 | 0.25 | 1.2 | 3.1 | 106 | 74 | 0.25–300 | 0.9998 |
Urine | 0.5 | 1.5 | 4.2 | 7.3 | 38 | 27 | 5.0–300 | 0.9986 |
Plasma | 1.0 | 3.0 | 3.2 | 8.6 | 23 | 16 | 10.0–300 | 0.9936 |