. Author manuscript; available in PMC: 2018 Jan 10.

Published in final edited form as: Semin Respir Crit Care Med. 2016 Mar 14;37(2):147–156. doi: 10.1055/s-0036-1572553

Table 1.

Human dendritic cell (DC) subsets and functions during HIV infection.

	Human skin DC subsets			Human blood DC subsets (cDC)			Human blood DC subsets (pDC)
DC subset	LC	CD14⁺DC	CD1a⁺DC	BDAC-1	BDAC3⁻	BDAC3⁺	CD123⁻pDC
Location	Epidermis Gut lumen	Dermis	Dermis	Blood	Blood Secondary lymphoid organs	Blood	Blood Secondary lymph organs Peripheral tissue (skin, lung, etc.)
Role in HIV infection	Degradation of HIV in Birbeck granules	HIV shuttle and transfer	HIV shuttle and transfer	HIV shuttle and transfer	Unknown	Unknown	Can be infected by HIV
Receptors and co-receptors	CD4, cc-chemokine receptor 5 (CCR5), and CXC-chemokine receptor (CXCR4)