Table 3. Adverse Events (AEs), Immune Related Adverse Events (IRAEs), and Overall Response Rates with PD-1 versus PD-L1 Inhibitors.

	PD-1 Inhibitors (n=3284)	PD-L1 Inhibitors (n=2460)	p-value
Overall AEs (%)	64	66	0.8
Grade 3-5 AEs (%)	13	21	0.15
Fatigue, any grade (%)	19	21	0.4
Diarrhea, any grade (%)	9	12	0.4
Rash, any grade (%)	9	7	0.8
IRAEs (%)	16	11	0.07
Grade 3-5 IRAEs (%)	3	5	0.4
Hypothyroidism, any grade (%)	6.7	4.2	0.07
Pneumonitis, any grade (%)	4	2	0.01
Colitis, any grade (%)	1.7	1	0.4
Overall Response Rate (ORR) (%)	19	18.6	0.17