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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Mult Scler. 2018 Jan;24(1):69–74. doi: 10.1177/1352458517737389

Figure 1. Cell-specific effects of DNMT and HDAC inhibitors.

Figure 1

Pharmacological inhibitors of DNA methyltransferases (DNMTs) or histone deacetylases (HDACs) have cell-specific effects. In oligodendrocyte lineage (OL) cells, they impair myelin formation and myelin repair, while in T cells they dampen inflammation and activation of immune responses