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IL-17 antiserum reduced spinal CaMKIIα activation in EAE mice. The level of phosphorylated CaMKIIα was enhanced in the spinal cords of EAE mice. Pretreatment of IL-17 antiserum decreased the CaMKIIα phosphorylation in EAE mice. Acute injection of IL-17 antiserum has no effect on the activation of CaMKIIα. Data are expressed as the mean ± SEM. *p < 0.05, **p < 0.01 compared with the sham immune group; #p < 0.05 compared with the vehicle-treated EAE group.
