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. 2014 Jul 17;5(1):12–17. doi: 10.1016/j.jpha.2014.07.004

Table 4.

Pharmacokinetic data of 2-oxo-clopidogrel after their oral administration in 8 subjects.

Parameter 2-Oxo-clopidogrel
Cmax (ng/mL) 6.8±0.9
Tmax (h) 1.8±3.4
t1/2 (h) 65±40
AUC0–24(ng h/mL) 89±10
AUC0−∞ (ng h/mL) 383±180

Cmax: maximum plasma concentration.

Tmax: time point of maximum plasma concentration.

t1/2: half life of drug elimination during the terminal phase.

AUC0–24: area under the plasma concentration–time curve from zero to 24 h.

AUC0–: area under the plasma concentration–time curve from zero hour to infinity.