Figure 2.

Reproductive hormone response in premenopausal women in the control and NK3Ra-treated cycles (n = 13). Mean serum (A) LH level during single timepoint sampling and (B) during 8 hours of frequent sampling every 10 minutes on day 6 to 7 of NK3Ra administration. (C) FSH level during single timepoint sampling and (D) during 8 hours of frequent sampling every hour on day 6 to 7 of NK3Ra administration. (E) Estradiol, (F) inhibin B secretion, and (G) urinary progesterone/creatinine ratio in premenopausal women (n = 11) adjusted to LH surge onset day 0 with and without NK3Ra was compared in premenopausal women by repeated measure two-way ANOVA at time points when paired data were available, followed by Bonferroni multiple comparisons post hoc analysis. Data are given as mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.