Table 5.
HRs and 95% CIs for Prenatal DES Exposure and Verified CVD Outcomes
| Condition |
DES-Exposed |
DES-Unexposed |
HRa (95% CI) | HRb (95% CI) | ||
|---|---|---|---|---|---|---|
| Participants, n (%) | Person-Years | Participants, n (%) | Person-Years | |||
| CAD | 28 (0.7) | 36,737 | 12 (0.7) | 16,203 | 1.72 (0.82–3.64) | 1.74 (0.82–3.68) |
| MI | 18 (0.5) | 36,828 | 5 (0.3) | 16,211 | 2.67 (0.93–7.66) | 2.63 (0.90–7.74) |
| Stroke | 12 (0.3) | 36,789 | 8 (0.5) | 16,254 | 0.92 (0.34–2.50) | 1.06 (0.37–3.04) |
| Total CVDc | 54 (1.4) | 36,412 | 26 (1.6) | 16,030 | 1.25 (0.75–2.09) | 1.31 (0.78–2.20) |
a
Adjusted for birth year and DES cohort.
b
Adjusted for birth year, cohort, BMI, smoking status, alcohol use, education, number of general physical examinations, age at menarche, menopausal status, and postmenopausal hormone use.
c
Includes women with CAD, MI, and/or stroke; the number of cases for the CVD category does not match the sum of the individual conditions because participants could have multiple conditions.