Table 2.
MetS Components, Y15, Y20, and Y25 (per SD) | mtDNAcn, Y15 and Y25 |
TL, Y15, Y20, and Y25 |
||||
---|---|---|---|---|---|---|
B | SE | P | B | SE | P | |
Waist circumference (per 13.8 cm) | −1.54 | 3.57 | 0.67 | −13.40 | 11.63 | 0.25 |
Triglycerides (per 1.21 mmol/L) | −4.35 | 2.20 | 0.05 | 4.70 | 8.92 | 0.60 |
HDL cholesterol (per 0.36 mmol/L) | 4.25 | 3.65 | 0.25 | 23.28 | 11.51 | 0.04 |
Systolic BP (per 13.7 mm Hg) | −0.16 | 3.20 | 0.96 | 18.61 | 10.74 | 0.08 |
Fasting glucose (per 0.72 mmol/L) | −2.28 | 4.55 | 0.62 | 9.66 | 11.15 | 0.39 |
Number of metabolic dysregulationsa | −1.88 | 2.64 | 0.48 | 2.90 | 8.77 | 0.74 |
MetS diagnosisb | 1.54 | 8.37 | 0.85 | 44.47 | 27.11 | 0.10 |
Adjusted for sex and time-varying age, education, race, smoking, alcohol, and physical activity.
Metabolic dysregulations defined as waist circumference >102 cm (men) or >88 cm (women); triglycerides >1.7 mmol/L; HDL cholesterol <1.03 mmol/L (men) or <1.30 mmol/L (women); systolic BP >130 or diastolic BP >85 mm Hg or antihypertensives; fasting plasma glucose >6.1 mmol/L or antidiabetic medication.
MetS defined as ≥3 dysregulations.