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. 2017 Oct 6;159(1):119–131. doi: 10.1210/en.2017-00565

Figure 1.

Figure 1.

Proliferation was not changed by neonatal exposure to BPA or E2. Proliferation was measured by Mki67 mRNA levels in (a) males and (b) females at PND7, demonstrating no statistically significant change in proliferation. Also, at 5 weeks, no statistically significant change was observed in proliferation in (c) males or (d) females (n = 3 to 6 for each sex). Circles represent individual mice, and average is represented by a line. Proliferation, as assessed by phosphorylated histone H3 expression in sections of PND7 females, was similar among (e) control-, (f) BPA0.05-, (g) BPA0.5-, and (h) BPA50-treated pituitary glands. Proliferation in male pituitary glands was also similar among (i) control, (j) BPA0.05, (k) BPA0.5, and (l) BPA50 exposure (n = 3 to 4 for each sex and each condition).